When Professor Pippy P. Poopypants comes to Jerome Horwitz Elementary School to teach science, and he goes off the deep end because students make fun of his name, only Captain Underpants can save the school from the professor's perilous plot.
A snotty situation ensues when Melvin Sneedley, an academically-gifted student, turns into the Bionic Booger Boy and must be stopped by George, Harold, and Captain Underpants. By flipping the pages, the reader may view animated illustrations.
Only Captain Underpants can stop the three evil space aliens who have invaded Jerome Horwitz Elementary School and turned everyone into lunchroom zombie nerds.