Sixteen-year-old Carmela Tofana finally gains access to her mother's apothecary in early 17th-century Rome, where she discovers that alongside healing remedies are dangerous potions that can change women's lives.
Rather than be split up into different foster homes, twelve-year-old Basil and his eleven-year-old sister Dahlia leap off a train which jump starts an adventure of ever-increasing mishaps and lands them in the kitchen of a cruel celebrity chef.
Despite her careful planning, eleven-year-old Jojo's first day of middle school unravels after an outfit mishap, caused by her cat-fluencer stepdad's new kitten, but as she tries hiding her embarrassment, she finds solace in new friends.
