Magically transported to southwest China to find the final object needed to break the spell on the wizard Merlin's beloved penguin, Jack and Annie take a side trip to the world's largest giant panda reserve.
Jack and Annie travel in their magic treehouse to the year 1621, where they celebrate the first Thanksgiving with the Pilgrims and Wampanoag Indians in the New Plymouth Colony.
Jack and Annie travel to a monastery in the Swiss Alps where, with the help of St. Bernard dogs and magic, they seek the second of four special objects necessary to break the spell on the wizard Merlin's beloved penguin, Penny.
The magic tree house takes Jack and Annie to a moon base in the future where they continue to search for the fourth thing they need to free their friend Morgan from the magician's spell.
While on a mission to prove to Merlin that they can use magic wisely, Jack and Annie travel to seventeenth-century Venice, Italy, to save the city from disaster.
Their magic tree house takes Jack and Annie back to a monastery in medieval Ireland, where they try to retrieve a lost book while being menaced by Viking raiders.
The magic treehouse takes Jack and Annie back two thousand years to ancient China where they must find the original copy of an old legend before the Imperial Library is burned down by the evil Dragon King.
Eight-year-old Jack, his seven-year-old sister, Annie, and Peanut the mouse ride in a tree house to the Amazon rain forests, where they encounter giant ants, flesh-eating piranhas, hungry crocodiles, and wild jaguars.