When her substitute teacher realizes she is struggling in math, Judy is sent to a math tutor at the local college and soon is completely into the spirit of college life.

Clementine's beloved teacher, Mr. D'Matz might be leaving for the rest of the year to go on a research trip to Egypt. The only solution, she decides, is to hatch a plan to get Mr. D'Matz back even if it means ruining his once-in-a-lifetime chance.

After learning about Sherlock Holmes, Humphrey the classroom hamster follows clues to try and discover why Mrs. Brisbane is gone and Mr. E., a fun but not very educational substitute, is taking her place in Room 26 at Longfellow School.

When Mr. Granite falls ill, A.J. and the gang endure a wacky week with a perpetually cheerful substitute teacher who wears a clown costume, uses hand puppets to talk, and uses magic tricks to saw students in half and make them disappear.

When his band votes him out due to his embarrasing musical antics, Dewey has to make the rent somehow. After intercepting a call for his substitute-teacher roomie Ned, Dewey finds himself in front of a class of elite elementary school students. Dewey decides to take on the music program and makes it his goal to teach them the gospel of rock and roll. His ulterior motive is to get them to compete against his former band for a cash prize.

There is an elegant substitute teacher in class today, but Katie's attempts to impress her keep going wrong.

When a sinister substitute teacher takes over their class, it is up to Eugene and the rest of the Sunnyview Superhero Squad to find Ms. Beasley and foil the sub's plot.

"Cat is not so keen on stepping in as substitute teacher at Kitty School, but he's surprised by how much he's able to teach the kittens--and how much he learns from them"--

Three seventh-graders at Ravens Pass Middle School cheat on a math test and think they have gotten away with it--until a very strange substitute teacher starts treating them in an ominous manner.

When his teacher is out sick for a week, Martin MacGregor has a difficult time with the homework assigned by the substitute teacher.